From the Guidelines
For pulmonary embolism treatment, Lovenox (enoxaparin) is typically administered at a dose of 1.0 mg/kg body weight subcutaneously every 12 hours or 1.5 mg/kg once daily. The dosing regimen for Lovenox is based on the patient's body weight, with two possible administration schedules 1. The options for dosing are as follows:
- 1.0 mg/kg every 12 hours
- 1.5 mg/kg once daily It is essential to accurately measure the patient's body weight to ensure proper dosing 1. Treatment with Lovenox usually continues for at least 5 days and until adequate oral anticoagulation with other medications is established. Patients should be monitored for signs of bleeding, and concurrent use of other anticoagulants or antiplatelet medications requires careful consideration 1. Proper injection technique is crucial, with administration into the anterolateral or posterolateral abdominal wall while the patient is sitting or lying down. In some cases, such as patients with cancer, other low molecular-weight heparins like Dalteparin may be used for extended treatment 1. However, for Lovenox, the recommended dosing regimens of 1.0 mg/kg every 12 hours or 1.5 mg/kg once daily are the standard for pulmonary embolism treatment 1.
From the Research
Dose of Lovenox for Pulmonary Embolism
- The dose of Lovenox (enoxaparin) for pulmonary embolism is not explicitly stated in the provided studies, but the following information can be inferred:
Enoxaparin Dosing Regimens
- A study published in 2003 2 used enoxaparin 1 mg/kg twice daily for 14 days during the acute phase, followed by 1.0 mg/kg or 1.5 mg/kg once daily during the chronic phase.
- A study published in 2016 3 compared once daily (1.5 mg/kg) and twice daily (1 mg/kg) enoxaparin dosing regimens for acute pulmonary embolism in cancer patients.
- A study published in 2005 4 used enoxaparin 1 mg/kg twice daily for 10-18 days, and then 1.5 mg/kg once daily until day 90.