What is the diagnosis for a 74-year-old male with atrial fibrillation (A-fib), coronary artery disease, hyperlipidemia, obesity, psoriasis, and asthma, presenting with right wrist pain, swelling, redness, warmth, and discomfort to touch, without fever, trauma, or recent high purine food intake, and a remote history of gout?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 25, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Right Wrist Pain

The patient presents with right wrist pain, swelling, redness, warmth to touch, and discomfort with touch, without any recent trauma or injury. Considering the patient's symptoms and medical history, the following differential diagnoses are possible:

  • Single most likely diagnosis
    • Cellulitis: The presence of erythema, warmth, swelling, and tenderness to touch, particularly on the palmar side of the wrist, is consistent with cellulitis, a common bacterial skin infection. The absence of fever does not rule out this diagnosis.
  • Other Likely diagnoses
    • Insect bite reaction: Despite the patient's denial of insect bites, the raised pinpoint area consistent with a bite suggests this possibility. The reaction could be causing the localized erythema, warmth, and swelling.
    • Contact dermatitis: Given the patient's history of psoriasis, they might be more prone to skin reactions, including contact dermatitis, which could cause similar symptoms.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Septic arthritis: Although the patient denies any trauma, septic arthritis is a serious condition that requires prompt diagnosis and treatment. The presence of swelling, redness, and warmth, especially in the context of a patient with multiple comorbidities, makes this a critical diagnosis not to miss.
    • Necrotizing fasciitis: This is a rare but life-threatening condition characterized by rapid progression of infection and necrosis of the fascia. The patient's symptoms of erythema, warmth, and swelling, along with the absence of trauma, should raise suspicion for this condition.
  • Rare diagnoses
    • Gout: Although the patient has a remote history of gout, the absence of recent high purine food intake and the lack of characteristic joint involvement (e.g., the big toe) make this diagnosis less likely. However, it cannot be entirely ruled out without further evaluation.
    • Rheumatoid arthritis flare: The patient's symptoms could be consistent with a rheumatoid arthritis flare, but there is no mention of a history of rheumatoid arthritis or other joint involvement, making this diagnosis less likely.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.