From the Guidelines
Ivermectin is not recommended for treating psoriatic arthritis. Psoriatic arthritis is an inflammatory joint condition associated with psoriasis that requires specific treatments targeting immune system pathways. Standard treatments for psoriatic arthritis include nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen for mild symptoms, disease-modifying antirheumatic drugs (DMARDs) such as methotrexate, and biologics like TNF inhibitors (adalimumab, etanercept) or IL-17 inhibitors (secukinumab) for more severe cases. Ivermectin is an antiparasitic medication primarily used to treat infections caused by certain parasites and has no established mechanism of action against the autoimmune inflammation that causes psoriatic arthritis.
Key Points to Consider:
- The American College of Rheumatology and National Psoriasis Foundation guideline for the treatment of psoriatic arthritis 1 does not mention ivermectin as a treatment option.
- The European League Against Rheumatism (EULAR) recommendations for the management of psoriatic arthritis with pharmacological therapies also do not include ivermectin 1.
- Ivermectin's lack of efficacy in treating autoimmune inflammation makes it an unsuitable choice for psoriatic arthritis, as stated in various studies 1. If you're experiencing symptoms of psoriatic arthritis, you should consult with a rheumatologist who can provide appropriate treatment options based on your specific condition, symptom severity, and medical history. Early treatment is important to prevent joint damage and manage symptoms effectively.
From the Research
Ivermectin for Psoriatic Arthritis
- There are no research papers to assist in answering this question as the provided studies do not investigate the use of ivermectin for psoriatic arthritis.
- The studies provided focus on other topics, including IL-23 inhibition for psoriatic arthritis 2, conventional disease-modifying anti-rheumatic drugs (DMARDs) for psoriatic arthritis 3, the TNF/IL-23/IL-17 axis in psoriasis treatment 4, methotrexate for psoriatic arthritis 5, and ivermectin for preventing and treating COVID-19 6.
- None of these studies examine the efficacy or safety of ivermectin for psoriatic arthritis, and therefore, no conclusions can be drawn about its potential use for this condition.