What is Kaloba (Pelargonium sidoides) syrup?

From the Guidelines

Kaloba syrup is a recommended treatment for upper respiratory tract infections, including sore throat, due to its efficacy and safety as demonstrated in high-quality studies, such as the meta-analysis by Timmer 1. The standard dosage for adults is typically 30 drops or 1.5 ml taken three times daily, while children aged 6-12 years should take 20 drops or 1 ml three times daily, and children aged 1-5 years should take 10 drops or 0.5 ml three times daily. Some key points to consider when using Kaloba syrup include:

• Treatment usually continues for 7-10 days or until symptoms improve
• Kaloba works by strengthening the immune system, preventing viruses and bacteria from attaching to cells in the respiratory tract, and exhibiting mild antibacterial and antiviral properties
• It may help reduce cough, congestion, and sore throat while potentially shortening illness duration
• Side effects are generally mild and may include mild gastrointestinal discomfort
• Patients should consult a healthcare provider before using Kaloba, especially if pregnant, breastfeeding, or taking other medications, as it may interact with blood thinners and medications metabolized by the liver, as noted in the study by Thomas 1. The evidence from the study by Perrott 1 also supports the use of Kaloba syrup as a safe and effective treatment for sore throat, with a low risk of adverse events. Overall, Kaloba syrup is a viable treatment option for sore throat, with a strong evidence base supporting its efficacy and safety, as demonstrated in the meta-analysis by Timmer 1.

From the Research

Kaloba Syrup Explanation

• Kaloba syrup, also known as Pelargonium sidoides extract, is a herbal remedy used to treat acute respiratory tract infections, including acute bronchitis, sinusitis, and the common cold 2, 3, 4, 5, 6.
• The syrup is made from the roots of the Pelargonium sidoides plant and is available in liquid or tablet form 2, 3, 4.
• Studies have shown that Kaloba syrup may be effective in alleviating symptoms of acute bronchitis in adults and children, as well as sinusitis in adults 2, 3, 5, 6.
• The syrup has been found to reduce the severity of symptoms, such as cough, sputum, and chest pain, and improve health-related quality of life 2, 3.
• Adverse events associated with Kaloba syrup are generally mild and rare, with no serious adverse events reported in clinical trials 2, 3, 5, 6.
• The efficacy and safety of Kaloba syrup have been evaluated in several clinical trials, including randomized, double-blind, placebo-controlled trials 2, 3, 4.
• The results of these trials suggest that Kaloba syrup may be a useful alternative to antibiotics for the treatment of acute bronchitis and other respiratory tract infections, although more research is needed to confirm its effectiveness 2, 3, 4, 5, 6.

Mechanism of Action

• The exact mechanism of action of Kaloba syrup is not fully understood, but it is thought to have anti-inflammatory and antimicrobial properties 2, 3.
• The syrup may help to reduce the severity of symptoms by inhibiting the production of pro-inflammatory cytokines and improving the function of the immune system 2, 3.

Dosage and Administration

• The recommended dosage of Kaloba syrup varies depending on the age and weight of the patient, as well as the severity of symptoms 3, 4.
• The syrup is typically taken three times a day, with a dose of 30 drops per administration 2, 3.
• It is recommended to consult with a healthcare professional before taking Kaloba syrup, especially if you have any underlying medical conditions or are taking other medications 2, 3, 4, 5, 6.