How is Calcigran (eclalcetide) administered?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 27, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Calcigran should be taken as an oral supplement, with a recommended dose of 1000 mg, taken 60 minutes before activity, to promote bone calcium balance and prevent disruptions to bone and calcium homeostasis, as supported by the most recent study 1. The standard formulation of Calcigran typically contains calcium carbonate, often combined with vitamin D, which helps with calcium absorption.

  • It's best taken with meals to enhance absorption, as stomach acid helps break down the calcium carbonate.
  • Patients should space their doses throughout the day rather than taking all tablets at once, as the body can only absorb limited amounts of calcium at one time.
  • The maximum dose of elemental calcium that should be taken at a time is 500 mg, as indicated by previous research 2.
  • Some patients may experience mild digestive side effects like constipation or gas when starting Calcigran.
  • It is essential to drink plenty of water when taking Calcigran and to follow the specific dosing instructions provided by your healthcare provider, as individual needs may vary based on age, medical conditions, and other medications being taken.
  • The most recent study 1 suggests that calcium supplementation before exercise attenuates the decrease in serum calcium and increase in PTH and bone resorption, highlighting the importance of proper timing and dosage of Calcigran intake.

References

Research

The effect of calcium supplementation on bone calcium balance and calcium and bone metabolism during load carriage in women: a randomised controlled crossover trial.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2025

Research

Calcium supplementation in clinical practice: a review of forms, doses, and indications.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2007

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.