What is the dose of Clexane (enoxaparin) in milliliters?

From the Guidelines

To determine the volume of Clexane (enoxaparin) in milliliters, you need to know the original dose in milligrams and the concentration of the Clexane preparation being used, which is typically 100 mg/mL or 150 mg/mL, as indicated in the studies 1. The prescribed dose should be divided by the concentration of the specific Clexane preparation to find the volume in milliliters. For instance, if the prescribed dose is 40 mg and the preparation is 100 mg/mL, the volume would be 0.4 mL. It's crucial to note that the exact volume to administer should be clearly indicated on the prescription or medication label, and for safety reasons, it's best to confirm the correct dose and volume with a healthcare provider or pharmacist, as incorrect dosing can lead to serious complications such as bleeding or inadequate anticoagulation, as discussed in the context of venous thromboembolism prophylaxis and treatment in patients with cancer 1. Key points to consider include:

• The concentration of Clexane preparations can vary, commonly 100 mg/mL or 150 mg/mL.
• The dose and volume should be confirmed with a healthcare provider or pharmacist to avoid errors.
• Incorrect dosing of anticoagulants like enoxaparin can have serious consequences, including bleeding or inadequate anticoagulation, highlighting the importance of precise dosing in clinical practice 1.

From the FDA Drug Label

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL NDC 11797-757-06 Enoxaparin Sodium Injection USP 30 mg/0.3 mL SINGLE-DOSE SYRINGES WITH AUTOMATIC SAFETY DEVICE FOR SUBCUTANEOUS INJECTION Ten 0.3 mL Syringes NDC 11797-758-06 Enoxaparin Sodium Injection USP 40 mg/0.4 mL SINGLE-DOSE SYRINGES WITH AUTOMATIC SAFETY DEVICE FOR SUBCUTANEOUS INJECTION Ten 0. 4 mL Syringes NDC 11797-759-06 Enoxaparin Sodium Injection USP 60 mg/0.6 mL SINGLE-DOSE SYRINGES WITH AUTOMATIC SAFETY DEVICE FOR SUBCUTANEOUS INJECTION Ten 0.6 mL Syringes NDC 11797-760-06 Enoxaparin Sodium Injection USP 80 mg/0.8 mL SINGLE-DOSE SYRINGES WITH AUTOMATIC SAFETY DEVICE FOR SUBCUTANEOUS INJECTION Ten 0. 8 mL Syringes NDC 11797-761-06 Enoxaparin Sodium Injection USP 100 mg/1 mL SINGLE-DOSE SYRINGES WITH AUTOMATIC SAFETY DEVICE FOR SUBCUTANEOUS INJECTION Ten 1 mL Syringes NDC 11797-762-06 Enoxaparin Sodium Injection USP 120 mg/0.8 mL SINGLE-DOSE SYRINGES WITH AUTOMATIC SAFETY DEVICE FOR SUBCUTANEOUS INJECTION Ten 0. 8 mL Syringes NDC 11797-763-06 Enoxaparin Sodium Injection USP 150 mg/1 mL SINGLE-DOSE SYRINGES WITH AUTOMATIC SAFETY DEVICE FOR SUBCUTANEOUS INJECTION Ten 1 mL Syringes

The amount of Clexane (enoxaparin) in mL is directly related to its dosage, with options including:

• 30 mg/0.3 mL
• 40 mg/0.4 mL
• 60 mg/0.6 mL
• 80 mg/0.8 mL
• 100 mg/1 mL
• 120 mg/0.8 mL
• 150 mg/1 mL 2

From the Research

Enoxaparin Dosage

• The standard dosage of enoxaparin is 40 mg once daily or 30 mg twice daily for the prevention of venous thromboembolic disorders 3.
• However, the dosage may vary depending on the patient's condition, such as renal impairment.
• For patients with renal impairment, the dosage of enoxaparin may need to be adjusted to prevent bleeding complications 4, 5, 6.

Conversion to mL

• Enoxaparin is typically administered subcutaneously in a dose of 40 mg (0.4 mL) once daily or 30 mg (0.3 mL) twice daily 3.
• To convert the dose to mL, we can use the following conversions:
  • 40 mg = 0.4 mL
  • 30 mg = 0.3 mL
• Therefore, the dose of enoxaparin in mL would depend on the prescribed dose in mg.

Specific Dosage Information

• Unfortunately, the provided studies do not specify the exact dosage of enoxaparin in mL for a particular patient or condition.
• However, the studies suggest that enoxaparin can be effective in preventing venous thromboembolic disorders when used at a dose of 40 mg once daily or 30 mg twice daily 3.
• It is essential to consult the prescribing information or a healthcare professional to determine the appropriate dosage of enoxaparin for a specific patient.