What are the differential diagnoses for anorectal pain?

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Rectal Pain Differential Diagnosis

The differential diagnosis for rectal pain is broad and can be categorized into several groups. Here's a breakdown of the possible causes:

  • Single most likely diagnosis
    • Anal fissure: This is a common cause of rectal pain, especially if the pain is sharp and worsens during or after bowel movements. The pain is often accompanied by bleeding.
  • Other Likely diagnoses
    • Hemorrhoids: Internal or external hemorrhoids can cause rectal pain, especially if they are thrombosed or prolapsed.
    • Proctalgia fugax: A condition characterized by sudden, severe rectal pain that lasts for a few seconds to minutes.
    • Levator ani syndrome: A condition that causes chronic or recurring rectal pain due to spasms of the levator ani muscle.
    • Rectal abscess: A collection of pus in the rectum that can cause pain, swelling, and fever.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Rectal cancer: Although less common, rectal cancer can cause rectal pain, especially if the tumor is large or has invaded surrounding tissues.
    • Ischemic proctitis: A condition caused by reduced blood flow to the rectum, which can lead to pain, bleeding, and potentially life-threatening complications.
    • Inflammatory bowel disease (IBD): Conditions like Crohn's disease or ulcerative colitis can cause rectal pain, diarrhea, and bleeding.
    • Infectious proctitis: Infections like gonorrhea, herpes, or HIV can cause rectal pain, discharge, and bleeding.
  • Rare diagnoses
    • Coccydynia: Pain in the coccyx (tailbone) that can radiate to the rectum.
    • Pudendal neuralgia: A condition that causes chronic pain in the distribution of the pudendal nerve, which can include the rectum.
    • Solitary rectal ulcer syndrome: A condition characterized by ulcers in the rectum, which can cause pain, bleeding, and difficulty with bowel movements.
    • Rectal endometriosis: A condition where endometrial tissue grows in the rectum, causing pain, bleeding, and other symptoms during menstruation.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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