From the Guidelines
Breastfeeding mothers should not take micronized purified flavonoid fraction (MPFF) without first consulting a healthcare provider due to insufficient research on its safety during lactation. The primary concern with any medication during breastfeeding is the potential impact on the developing infant, whose detoxification systems are still immature and may process substances differently than adults 1. While limited data suggests that flavonoids in general may pass into breast milk in small amounts, there is a lack of specific research on MPFF during breastfeeding to guarantee its safety.
Some key points to consider include:
- The potential benefits of MPFF for conditions like venous insufficiency and hemorrhoids, which can affect postpartum women, must be weighed against any potential risks to the infant 1.
- Healthcare providers may recommend alternative treatments with better-established safety profiles during lactation, such as sitz baths, dietary changes, or other medications known to be compatible with breastfeeding.
- The pathogenesis of conditions like hemorrhoids is complex and multifactorial, involving factors such as inadequate fiber intake, prolonged sitting on the toilet, and chronic straining at stool, although rigorous proof of these beliefs is lacking 1.
- The use of MPFF, also known as micronized purified flavonoid fraction, is typically prescribed for venous insufficiency and hemorrhoids, and its safety during breastfeeding is not well established 1.
Given the lack of specific research on MPFF during breastfeeding, it is essential for breastfeeding mothers to consult with their healthcare provider before taking this medication to discuss potential risks and benefits and explore alternative treatment options.
From the Research
Micronized Purified Flavonoid Fraction and Breastfeeding
- There is no direct evidence in the provided studies that addresses the safety of taking micronized purified flavonoid fraction while breastfeeding 2, 3, 4, 5.
- However, one study discusses the benefits of breastfeeding and how clinicians can support postdischarge breastfeeding, but it does not mention micronized purified flavonoid fraction 6.
- The studies primarily focus on the use of micronized purified flavonoid fraction for the treatment of chronic venous disease, its benefits, and its effects on patients with this condition 2, 3, 4, 5.
- Since there is no direct evidence on the use of micronized purified flavonoid fraction during breastfeeding, it is essential to consult a healthcare professional for guidance on taking this medication while breastfeeding.