Can a 20-month-old child with vomiting and an elevated blood urea nitrogen (BUN) to creatinine ratio of 38.3 be diagnosed with gastroenteritis?

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Last updated: May 28, 2025View editorial policy

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Differential Diagnosis for a 20-month-old with Vomiting and a BUN/Creatinine Ratio of 38.3

  • Single most likely diagnosis:
    • Gastroenteritis: This is the most likely diagnosis given the symptoms of vomiting and the elevated BUN/creatinine ratio, which can indicate dehydration, a common complication of gastroenteritis in children.
  • Other Likely diagnoses:
    • Dehydration: This can be a direct consequence of vomiting and can lead to the observed laboratory findings.
    • Urinary Tract Infection (UTI): Although less common in this age group without other symptoms, a UTI could potentially cause an elevation in the BUN/creatinine ratio.
    • Acute Gastrointestinal Infection with dehydration: Similar to gastroenteritis, other infections causing vomiting can lead to dehydration and the observed lab results.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.):
    • Diabetic Ketoacidosis (DKA): Although less likely without a history of diabetes, DKA can present with vomiting and dehydration, and the BUN/creatinine ratio can be elevated. Missing this diagnosis can be fatal.
    • Intussusception: A condition where a part of the intestine slides into an adjacent part, which can cause vomiting and dehydration. It's a surgical emergency.
    • Volvulus or other intestinal obstruction: These conditions can cause severe vomiting and dehydration, and require immediate surgical intervention.
  • Rare diagnoses:
    • Congenital adrenal hyperplasia: A rare condition that can cause dehydration and electrolyte imbalances, potentially leading to an elevated BUN/creatinine ratio.
    • Renal vein thrombosis: A rare condition in children that can cause acute kidney injury, presenting with vomiting and dehydration among other symptoms.
    • Inborn errors of metabolism: Certain metabolic disorders can present with vomiting, dehydration, and abnormal laboratory findings, including an elevated BUN/creatinine ratio.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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