What causes pain in the fifth metatarsal bone?

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Last updated: May 28, 2025View editorial policy

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From the Guidelines

Fifth metatarsal pain should be initially managed with the RICE method, over-the-counter pain relievers, and avoidance of high-impact activities, with consideration for X-ray imaging if pain persists or worsens, as recommended by the Ottawa ankle rules and other clinical guidelines 1. To manage fifth metatarsal pain, it is essential to follow a step-by-step approach.

  • Rest the foot and avoid activities that aggravate the pain.
  • Apply ice for 15-20 minutes several times daily to reduce inflammation.
  • Compress the foot with an elastic bandage to provide support.
  • Elevate the foot when possible to reduce swelling. Additionally, taking over-the-counter pain relievers like ibuprofen (400-600mg every 6-8 hours) or acetaminophen (500-1000mg every 6 hours) can help reduce pain and inflammation 1. It is crucial to wear supportive shoes with cushioning and avoid high-impact activities until the pain subsides. If the pain persists beyond 1-2 weeks, worsens with walking, or is accompanied by visible swelling or bruising, it is essential to seek medical attention, as an X-ray may be necessary to rule out a fracture, following the guidelines outlined in the Ottawa ankle rules and other clinical decision rules, such as the Bernese ankle rules 1. A healthcare provider may recommend a walking boot, crutches, or in severe cases, surgical intervention. Fifth metatarsal pain often results from overuse, improper footwear, or sudden increases in activity level, so gradually increasing exercise intensity and wearing proper footwear can help prevent recurrence, as suggested by the American College of Radiology guidelines 1.

From the Research

Fifth Metatarsal Pain

  • Fifth metatarsal pain can be caused by various factors, including fractures, deformities, and gait mechanics 2, 3.
  • Metatarsalgia, a common condition characterized by pain in the forefoot, can also contribute to fifth metatarsal pain, although it typically affects the second through fourth metatarsal heads 2.
  • Fractures of the fifth metatarsal bone are common, with approximately 30% of metatarsal fractures affecting the base of the fifth metatarsal bone 4.

Treatment Options

  • Treatment for fifth metatarsal fractures depends on the location and severity of the fracture, as well as the patient's overall health and activity level 4, 5.
  • Early functional therapy is recommended for fractures in zones I and II, while surgical treatment is often necessary for fractures in zone III 4.
  • Nonsurgical management, including immobilization and physical therapy, can be effective for some patients, while others may require surgical intervention, such as intramedullary screw fixation or plate fixation 6.

Specific Considerations

  • Jones fractures, which occur at the metaphyseal-diaphyseal junction of the fifth metatarsal, are at increased risk for nonunion and continued pain, and may require specialized treatment, including biologic augmentation and primary bone grafting 6.
  • Rehabilitation protocols, orthoses, and shoe wear suggestions can help optimize patient outcomes and reduce the risk of complications 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Metatarsalgia.

The Journal of the American Academy of Orthopaedic Surgeons, 2010

Research

Metatarsal fractures.

Clinics in podiatric medicine and surgery, 2010

Research

Fifth metatarsal fractures and current treatment.

World journal of orthopedics, 2016

Research

Fifth Metatarsal Jones Fractures: Diagnosis and Treatment.

The Journal of the American Academy of Orthopaedic Surgeons, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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