Differential Diagnosis for Red Rash on the Palm of the Hand
Single Most Likely Diagnosis
- Dyshidrotic Eczema (Pompholyx): This condition is characterized by small, itchy blisters on the palms of the hands or soles of the feet. It's a common cause of a red rash in these areas, often related to stress, allergies, or environmental factors.
Other Likely Diagnoses
- Contact Dermatitis: An allergic reaction or irritation from substances like soap, detergent, or certain metals can cause a red rash on the palms.
- Psoriasis: Although less common on the palms, psoriasis can cause red, scaly patches in this area, especially in patients with a history of the condition.
- Palmar Erythema: This condition involves reddening of the palms due to increased blood flow and can be associated with various factors, including pregnancy, liver disease, or thyroid disorders.
Do Not Miss Diagnoses
- Secondary Syphilis: A rash on the palms of the hands can be a sign of secondary syphilis, a sexually transmitted infection. Missing this diagnosis could lead to severe complications if left untreated.
- Lyme Disease: Although the characteristic "bull's-eye" rash of Lyme disease typically appears on the trunk, arms, or legs, it can occasionally occur on the palms. Early diagnosis is crucial to prevent long-term consequences.
Rare Diagnoses
- Keratoderma Blennorrhagicum: A rare condition associated with Reiter's syndrome, characterized by a rash on the palms and soles, often accompanied by arthritis and urethritis.
- Pityriasis Rubra Pilaris: A rare skin disorder that can cause a red rash on the palms, among other areas, and is often accompanied by scaling and thickening of the skin.