What are the causes of mucus in stool?

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Last updated: May 28, 2025View editorial policy

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From the Guidelines

Mucus in stool is most commonly caused by inflammatory bowel diseases, irritable bowel syndrome (IBS), infections, food allergies or intolerances, and colorectal cancer, as evidenced by the European consensus on the histopathology of inflammatory bowel disease 1. The presence of mucus in stool can be a normal occurrence, but persistent or large amounts warrant medical attention. Common causes of mucus in stool include:

  • Inflammatory bowel diseases like Crohn's disease or ulcerative colitis
  • Irritable bowel syndrome (IBS)
  • Infections such as bacterial or parasitic gastroenteritis
  • Food allergies or intolerances
  • Colorectal cancer If you notice mucus in your stool, especially if accompanied by other symptoms like abdominal pain, diarrhea, blood in stool, or weight loss, consult a healthcare provider. Treatment depends on the underlying cause and may include antibiotics for infections, anti-inflammatory medications for IBD (such as mesalamine, corticosteroids, or biologics), dietary changes for food intolerances, or antispasmodics for IBS, as suggested by the american gastroenterological association medical position statement: irritable bowel syndrome 1. Mucus production occurs naturally in the intestines to protect and lubricate the digestive tract, but excessive production often indicates inflammation or irritation of the intestinal lining. Keeping a food diary and noting symptom patterns can help identify potential triggers and assist your healthcare provider in determining the appropriate diagnosis and treatment plan. It is essential to note that the diagnosis of a functional bowel disorder always presumes the absence of a structural or biochemical explanation for the symptoms, as stated in the american gastroenterological association medical position statement: irritable bowel syndrome 1. Therefore, a thorough evaluation, including a complete physical examination, sigmoidoscopy, and additional testing when indicated, is necessary to determine the underlying cause of mucus in stool. The european consensus on the histopathology of inflammatory bowel disease 1 provides a comprehensive overview of the microscopic features used for the diagnosis of IBD, which can aid in the diagnosis and treatment of mucus in stool. In summary, the most appropriate course of action for mucus in stool is to consult a healthcare provider to determine the underlying cause and develop a treatment plan, as excessive mucus production can be a sign of an underlying condition that requires medical attention 1.

From the Research

Causes of Mucous in Stool

  • Inflammatory bowel disease (IBD) is a common cause of mucous in stool, as it leads to inflammation and irritation in the digestive tract 2, 3, 4, 5, 6
  • Specific conditions such as ulcerative colitis and Crohn's disease can cause mucous in stool due to the inflammation and damage they cause to the colon and rectum 2, 3, 4, 5, 6
  • The exact mechanism of mucous production in IBD is not fully understood, but it is thought to be related to the inflammation and immune response in the gut 3, 6
  • Certain medications, such as sulfasalazine and mesalamine, can help reduce inflammation and mucous production in IBD patients 2, 3, 5, 6

Related Factors

  • Bacterial imbalance and infection can contribute to mucous production in the gut 2, 4
  • Dietary factors, such as a high-fiber diet, can help reduce mucous production and inflammation in IBD patients 4
  • Stress and emotional factors can exacerbate IBD symptoms, including mucous production 4

Treatment and Management

  • Medications such as 5-aminosalicylates, corticosteroids, and immunomodulators can help reduce inflammation and mucous production in IBD patients 2, 3, 4, 5, 6
  • Lifestyle changes, such as a healthy diet and stress management, can help manage IBD symptoms and reduce mucous production 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Mesalamine for inflammatory bowel disease: recent reappraisals.

Inflammation & allergy drug targets, 2008

Research

Mesalazine in inflammatory bowel disease: a trendy topic once again?

Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2010

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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