Is tamsulosin (generic name) recommended before knee replacement surgery?

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Last updated: May 28, 2025View editorial policy

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From the Research

Tamsulosin should typically be continued before knee replacement surgery, but this decision should be confirmed with your surgeon and anesthesiologist during pre-operative evaluation. The standard recommendation is to take your regular dose of tamsulosin (usually 0.4 mg once daily) up to and including the morning of surgery. Tamsulosin is an alpha-blocker used to treat benign prostatic hyperplasia (BPH) by relaxing muscles in the prostate and bladder neck, which helps improve urination. Abruptly stopping tamsulosin before surgery could lead to urinary retention complications, particularly since urinary catheters are often placed during joint replacement procedures. Additionally, tamsulosin does not significantly increase bleeding risk or interact with most anesthetics used during orthopedic surgery. However, your surgical team may have specific protocols based on your individual health status, other medications you take, or the particular surgical approach planned for your knee replacement. Be sure to provide a complete medication list during your pre-operative appointment and follow any specific instructions given by your surgical team regarding medication management. Some studies, such as 1, have shown that tamsulosin can reduce the risk of postoperative urinary retention, which is a common complication after surgery. However, other studies, such as 2, have found that prophylactic tamsulosin does not reduce the incidence of postoperative urinary retention after hip and knee arthroplasty. It's essential to consider the most recent and highest-quality study, which is 1, and follow the recommendation of continuing tamsulosin before knee replacement surgery, while also considering individual patient factors and surgical team protocols. Key points to consider include:

  • Tamsulosin is an effective treatment for BPH, as shown in studies such as 3 and 4
  • The medication can help improve urination and reduce the risk of urinary retention complications
  • Tamsulosin does not significantly increase bleeding risk or interact with most anesthetics used during orthopedic surgery
  • Individual patient factors, such as health status and other medications, should be considered when making decisions about tamsulosin use before surgery.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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