What is the cause of a sensation of a bubble in the chest?

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Last updated: May 28, 2025View editorial policy

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Differential Diagnosis for Feeling a Bubble in the Chest

  • Single most likely diagnosis
    • Gastroesophageal reflux disease (GERD): This condition is characterized by the backflow of stomach acid into the esophagus, which can cause a sensation of a bubble or discomfort in the chest.
  • Other Likely diagnoses
    • Esophageal spasm: Abnormal muscle contractions in the esophagus can cause a feeling of a bubble or lump in the chest.
    • Anxiety or panic disorder: These conditions can cause chest tightness or a sensation of a bubble, often accompanied by other symptoms like shortness of breath or palpitations.
    • Hiatal hernia: A protrusion of the stomach through the diaphragm can cause reflux and discomfort, potentially leading to a feeling of a bubble in the chest.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Pulmonary embolism: A blood clot in the lungs can cause sudden, severe chest pain and discomfort, which might be described as a feeling of a bubble.
    • Myocardial infarction (heart attack): Chest pain or discomfort, including a sensation of a bubble, can be a symptom of a heart attack.
    • Aortic dissection: A tear in the aorta can cause severe, sudden chest pain, which might be described as a feeling of a bubble or tearing sensation.
  • Rare diagnoses
    • Esophageal diverticulum: A pouch-like protrusion in the esophagus can cause symptoms like difficulty swallowing and chest discomfort, potentially leading to a feeling of a bubble.
    • Boerhaave syndrome: A rare condition characterized by a spontaneous rupture of the esophagus, which can cause severe chest pain and discomfort.
    • Pneumomediastinum: Air in the mediastinum (the space between the lungs) can cause chest pain and discomfort, potentially leading to a feeling of a bubble.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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