Are you still covered against pregnancy if you took your progesterone-only pill (POP) at 5:40 in Amsterdam time yesterday and 20:15 in UK time today?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 28, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

You are not fully protected against pregnancy due to the timing of your progesterone-only pill (POP) doses. The time difference between your doses (approximately 38.5 hours, considering the 1-hour time zone difference between Amsterdam and the UK) exceeds the recommended interval for POPs, as a dose is considered missed if it has been >3 hours since it should have been taken 1. Progesterone-only pills need to be taken within a strict time frame each day, and the protection begins to decrease after this window.

To understand the implications, consider the following key points:

  • A missed dose is defined as one that is taken more than 3 hours late 1.
  • Peak serum steroid levels are reached about 2 hours after administration, followed by rapid distribution and elimination, such that by 24 hours after administration, serum steroid levels are near baseline 1.
  • An estimated 48 hours of POP use was deemed necessary to achieve the contraceptive effects on cervical mucus 1.

Given this information, to restore full contraceptive protection, continue taking your pills at the same time each day going forward, and use a backup contraception method like condoms for the next 48 hours, as recommended for missed POPs 1. If you had unprotected sex during this period of reduced protection, you might want to consider emergency contraception and consult with a healthcare provider about your specific situation and pill formulation.

From the Research

Understanding Progesterone-Only Contraceptive Pills

  • Progesterone-only contraceptive pills are a type of birth control that contains only progestin, which is a synthetic form of the hormone progesterone 2, 3.
  • These pills work by thickening the mucus in the cervix, making it harder for sperm to reach the egg, and also by preventing ovulation in some cases.

Time Zone and Contraceptive Pill Timing

  • Amsterdam is in the Central European Time (CET) zone, which is 1 hour ahead of the UK time zone (Greenwich Mean Time, GMT) during standard time and 2 hours ahead during daylight saving time.
  • Assuming the times given are in standard time, 5:40 AM in Amsterdam would be 4:40 AM in the UK.
  • Taking the pill at 5:40 AM in Amsterdam and then at 20:15 (8:15 PM) in the UK time the next day means there is approximately a 27-hour gap between the two doses, considering the time difference.

Contraceptive Coverage

  • The general guideline for taking progesterone-only pills is to take them at the same time every day to maintain contraceptive coverage 4, 5.
  • Missing a pill or taking it more than 3 hours late can reduce the effectiveness of the contraceptive and may require additional contraceptive measures, such as emergency contraception, if unprotected sex occurs 6.
  • Given the 27-hour gap between doses in this scenario, it's possible that contraceptive coverage may be compromised, especially if the gap exceeds the recommended 3-hour window for progesterone-only pills.

Emergency Contraception

  • If there's concern about contraceptive coverage due to missed or delayed pills, emergency contraception can be considered to prevent pregnancy after unprotected sex 2, 3, 4, 5, 6.
  • Emergency contraception methods include oral medications like levonorgestrel and ulipristal, and the insertion of a copper intrauterine device (IUD), which can be effective when used within a certain timeframe after unprotected sex.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Practice Bulletin No. 152: Emergency Contraception.

Obstetrics and gynecology, 2015

Research

Emergency contraception: which is the best?

Minerva ginecologica, 2016

Research

Emergency contraception - potential for women's health.

The Indian journal of medical research, 2014

Research

Emergency Contraception.

Pediatrics, 2019

Related Questions

What is the maximum delay allowed when taking Slynd (Drospirenone) birth control medication for it to remain effective?
What is the emergency pill (Emergency Contraception) and how is it taken?
What should be done if a dose of the progesterone-only pill (POP) is missed and not taken until 9:40pm, having previously taken it at 6pm every day?
Does vaginal douching (intrauterine cleansing) help prevent pregnancy after contraceptive (birth control) failure?
What are the risks of pregnancy if I took my progesterone-only pill at 5:40 CET and 20:15 GMT, having had sex 2 days prior?
What tests or imaging are recommended for bilateral popliteal fossa tightness with tenderness, worse on the right side?
How to complete orthostatic (postural) vital signs?
What are the potential interactions between Humacology 0:110 CBD (Cannabidiol) Isolate 'YELLOW' Pastilles and Humacology 'BLACK' 0:250:60:20 Broad Spectrum CBD (Cannabidiol)+CBN (Cannabinol)+CBC (Cannabichromene) Oil in a patient concurrently taking Effexor (Venlafaxine) and Ritalin (Methylphenidate)?
What is the protocol for pregnant inpatient detoxification, including treatment with Buprenorphine (Suboxone) or Buprenorphine (Subutex) for opioid, alcohol, and Lorazepam (Ativan) dependence?
Is contraceptive coverage maintained after taking a progesterone-only pill (POP) at 5:40 Amsterdam time yesterday and 20:15 UK time today, with last sexual intercourse 2 days ago?
What is the interaction between CBD (Cannabidiol) isolate and Ritalin (Methylphenidate)?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.