From the Guidelines
I strongly advise against combining "BLACK" CBD+CBN+CB product with Effexor (venlafaxine) 37.5mg for insomnia without medical supervision, as this combination may increase the risk of adverse effects and reduce the effectiveness of the prescribed medication. The use of CBD products with Effexor may lead to increased blood levels of venlafaxine, resulting in side effects such as dizziness, drowsiness, or serotonin syndrome in severe cases 1. Additionally, the broad spectrum CBD product contains multiple cannabinoids whose combined effects with Effexor are not well-studied.
Some key points to consider:
- The American Academy of Sleep Medicine recommends cognitive behavioral therapy for insomnia (CBT-I) as a standard of treatment, with pharmacotherapy considered mainly in patients who are unable to derive benefit from CBT-I 1.
- The 2019 U.S. Department of Veterans Affairs and U.S. Department of Defense clinical practice guidelines advise against the use of benzodiazepines, trazodone, antihistamines, and antipsychotics for the treatment of chronic insomnia disorder due to their adverse effect profiles and limited evidence of efficacy 1.
- When considering pharmacologic treatment for insomnia, it is essential to weigh the potential benefits against the risks of adverse effects, particularly in older adults or those with comorbidities.
Given the potential risks and limited evidence of efficacy, it is crucial to consult a healthcare provider before combining "BLACK" CBD+CBN+CB product with Effexor (venlafaxine) 37.5mg for insomnia. They can provide guidance on approved sleep aids, potential timing adjustments of the medication, or alternative treatments such as CBT-I or improved sleep hygiene practices.
From the Research
CBD and Sleep
- The use of CBD for sleep disorders has been studied, with some evidence suggesting its potential therapeutic effects 2, 3, 4.
- A study found that a cannabinoids supplement containing CBD improved sleep quality and efficiency in adults with subthreshold insomnia 3.
- However, another study noted that the evidence for CBD's therapeutic efficacy is often mixed and lacks well-powered randomized, placebo-controlled studies 5.
CBD and Insomnia
- CBD may have therapeutic potential for the treatment of insomnia, with preliminary research suggesting its potential benefits 4.
- A study found that a cannabinoids supplement containing CBD improved insomnia symptoms in adults with subthreshold insomnia 3.
- However, the long-term effects of CBD on sleep and insomnia are not well understood and require further research 6.
Interactions with Effexor
- There is limited research on the interactions between CBD and Effexor (venlafaxine) specifically.
- However, a study noted that cannabinoids can interact with other medications, including antidepressants, and may increase the risk of adverse effects 5.
- It is essential to consult with a healthcare professional before using CBD with Effexor or any other medication.
Broad Spectrum CBD+CBN+CB
- Broad spectrum CBD products, which contain multiple cannabinoids, including CBD, CBN, and CB, may have different effects on sleep and insomnia compared to CBD alone 6.
- A study found that a cannabinoids supplement containing CBD, CBN, and other cannabinoids improved sleep quality and efficiency in adults with subthreshold insomnia 3.
- However, the specific effects of broad spectrum CBD+CBN+CB products on sleep and insomnia are not well understood and require further research.