From the Guidelines
Vantin is the brand name for cefpodoxime proxetil in the United States. This medication is a third-generation cephalosporin antibiotic that comes in oral tablet and suspension forms. Vantin is used to treat various bacterial infections including respiratory tract infections, skin infections, urinary tract infections, and certain sexually transmitted infections. The medication works by inhibiting bacterial cell wall synthesis, which ultimately kills the bacteria causing the infection. Cefpodoxime proxetil is actually a prodrug that gets converted to its active form, cefpodoxime, in the body after absorption.
Key Points
- Typical adult dosing ranges from 100-400 mg taken twice daily, depending on the type and severity of infection being treated, while children's dosing is based on weight 1.
- Patients should take the full course of antibiotics as prescribed, even if symptoms improve before completion, to prevent antibiotic resistance and ensure complete eradication of the infection.
- Cefpodoxime proxetil has a similar spectrum of activity to ceftriaxone and is often regarded as the preferred treatment for patients in whom treatment with high-dose amoxicillin or amoxicillin/clavulanate fails 1.
- The clinical utility of cefpodoxime proxetil is limited by its poor taste in suspension form, which can affect adherence in children 1.
Considerations
- The choice of antibiotic should be based on the likely bacterial pathogens and the patient's medical history, including any allergies or previous antibiotic use 1.
- Cefpodoxime proxetil is a suitable agent for the treatment of acute bacterial sinusitis, but its use should be guided by local resistance patterns and patient-specific factors 1.
From the FDA Drug Label
200 mg Label – 100 Count NDC 0781-5439-01 Cefpodoxime Proxetil Tablets, USP 200 mg* Rx only 100 Tablets SANDOZ
The brand name for cefpodoxime proxetil is not explicitly stated in the provided text, however SANDOZ is mentioned which could be a brand or manufacturer name.
- Key points:
- The text does mention Cefpodoxime Proxetil Tablets, USP which is the drug name.
- SANDOZ is the only name that resembles a brand name in the provided text 2.
From the Research
Brand Name for Cefpodoxime Proxetil
- The brand name for cefpodoxime proxetil is not explicitly mentioned in the provided studies 3, 4, 5, 6, 7.
Uses of Cefpodoxime Proxetil
- Cefpodoxime proxetil is used to treat various bacterial infections, including:
Pharmacokinetics and Therapeutic Uses
- Cefpodoxime proxetil is an orally administered prodrug that is absorbed and de-esterified by the intestinal mucosa to release the third-generation cephalosporin, cefpodoxime 3.
- The drug has a broad spectrum of antibacterial activity and is stable towards the most commonly found plasmid-mediated beta-lactamases 3.
- Cefpodoxime proxetil is generally well tolerated, with mild to moderate gastrointestinal disturbances occurring in 4 to 15% of patients treated with therapeutic doses 3.