What are the differential diagnoses for a patient presenting with tachycardia (heart rate of 135 beats per minute)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 29, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for a Heart Rate of 135

The patient's heart rate of 135 beats per minute (bpm) is significantly elevated, suggesting a range of potential causes. Here's a categorized differential diagnosis:

  • Single Most Likely Diagnosis
    • Dehydration or Hypovolemia: This is often a common and straightforward cause of tachycardia. Dehydration can lead to a decrease in blood volume, triggering the body to increase heart rate to maintain adequate circulation.
  • Other Likely Diagnoses
    • Anxiety or Panic Attack: Anxiety and panic attacks can cause significant increases in heart rate due to the body's stress response.
    • Infection or Sepsis: Systemic infections can lead to tachycardia as part of the body's inflammatory response.
    • Thyroid Storm: Hyperthyroidism, particularly in its acute presentation known as thyroid storm, can cause marked tachycardia.
    • Cardiac Conditions (e.g., Myocardial Infarction, Cardiomyopathy): Various heart conditions can lead to an elevated heart rate as the heart works harder to compensate for reduced efficiency or damage.
  • Do Not Miss Diagnoses
    • Pulmonary Embolism: Although less common, a pulmonary embolism is a life-threatening condition that can present with tachycardia and requires immediate diagnosis and treatment.
    • Cardiac Tamponade: This is a serious medical condition where fluid accumulates in the sac around the heart, impeding its ability to pump effectively, and can present with tachycardia among other symptoms.
    • Hemorrhage: Internal or external bleeding can lead to hypovolemic shock, characterized by tachycardia, among other signs.
  • Rare Diagnoses
    • Pheochromocytoma: A rare tumor of the adrenal gland that can cause episodes of severe hypertension and tachycardia due to excessive catecholamine release.
    • Neurogenic Causes (e.g., Subarachnoid Hemorrhage): Certain neurological conditions can affect the autonomic nervous system, leading to abnormal heart rate regulation.
    • Drug-Induced Tachycardia: Various medications and substances (prescription, over-the-counter, or illicit) can cause tachycardia as a side effect.

Each of these diagnoses requires careful consideration of the patient's overall clinical presentation, medical history, and additional diagnostic tests as necessary to determine the underlying cause of the elevated heart rate.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.