From the Research
For subacute thyroiditis, naproxen is typically prescribed at a dose of 500 mg twice daily with food, as this dose has been shown to be effective in reducing inflammation and alleviating symptoms 1. The treatment usually continues for 2-4 weeks, with gradual tapering as symptoms improve. Some patients may require a longer duration of therapy depending on symptom severity and response.
- Naproxen works by reducing inflammation in the thyroid gland, which helps alleviate pain and tenderness.
- It's essential to take naproxen with food to minimize gastrointestinal side effects.
- If naproxen alone doesn't provide adequate relief, prednisone (starting at 15 mg daily with tapering over 2-4 weeks) may be added, as suggested by a recent study 2. During treatment, monitor for improvement in symptoms such as neck pain, fever, and fatigue.
- Patients should be aware that naproxen may cause stomach upset, heartburn, or dizziness, and should avoid alcohol while taking this medication.
- Regular follow-up is recommended to assess thyroid function, as subacute thyroiditis can progress through hyperthyroid and hypothyroid phases before resolution 3, 4.