From the Research
Keflex (cephalexin) is not recommended as a first-line treatment for a stye that hasn't responded to erythromycin ointment, due to the lack of evidence supporting its effectiveness in this context. When considering the treatment of a stye, it's essential to prioritize morbidity, mortality, and quality of life as outcomes. The most recent and highest quality study, 1, suggests that systemic antibiotics, including cephalexin, do not significantly improve the percentage of patients with complete resolution of their abscesses when given in addition to incision and drainage.
Key Considerations
- The study 1 included 589 patients and found no significant difference in cure rates between those treated with systemic antibiotics and those who received a placebo.
- Another study, 2, although not directly related to stye treatment, highlights the importance of incision and drainage in managing abscesses, which may be relevant in some cases of styes that have progressed to abscess formation.
- It's crucial to note that the use of antibiotics should be judicious and based on the most current evidence to minimize the risk of antibiotic resistance and other adverse effects.
Treatment Approach
- For a stye that hasn't responded to erythromycin ointment, consider alternative treatments that prioritize reducing symptoms and promoting healing, such as continued use of warm compresses and good hygiene practices.
- If the stye persists or worsens, reassessment by a healthcare provider is necessary to determine the best course of action, which may include further diagnostic testing or alternative treatments.