What is the cause of a swollen and erythematous (red) inner ankle?

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Differential Diagnosis for Swollen and Red Inner Ankle

  • Single most likely diagnosis
    • Ankle sprain: This is the most common cause of a swollen and red inner ankle, often resulting from inversion injuries that stretch or tear the ligaments on the inner aspect of the ankle.
  • Other Likely diagnoses
    • Cellulitis: A bacterial skin infection that can cause redness, swelling, and warmth, often spreading from a break in the skin.
    • Achilles tendonitis: Inflammation of the Achilles tendon, which can cause pain, swelling, and redness in the back of the ankle, potentially radiating to the inner aspect.
    • Gout or pseudogout: These conditions involve the deposition of urate crystals (gout) or calcium pyrophosphate dihydrate crystals (pseudogout) within the joints, leading to acute inflammatory arthritis, which can affect the ankle joint.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed)
    • Deep vein thrombosis (DVT): Although less common, DVT can cause swelling and redness in the ankle and leg, and if missed, can lead to life-threatening pulmonary embolism.
    • Osteomyelitis: A bone infection that can cause pain, redness, and swelling, often requiring prompt antibiotic treatment to prevent serious complications.
    • Septic arthritis: A joint infection that can cause severe pain, swelling, and redness, requiring immediate medical attention to prevent joint destruction.
  • Rare diagnoses
    • Erythema nodosum: An inflammatory condition characterized by the formation of nodules under the skin, often on the shins, but can occasionally affect the ankles.
    • Sarcoidosis: A systemic disease that can cause inflammation in various parts of the body, including the joints and skin, leading to swelling and redness in the ankles.
    • Rheumatoid arthritis: Although more commonly affecting the hands and feet, rheumatoid arthritis can also involve the ankles, causing swelling, redness, and pain.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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