What is the cause of a patient's chest pain and numbness headaches, with a normal electrocardiogram (EKG) and no signs of stroke, who has a pacemaker (permanent artificial cardiac pacemaker)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 22, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Chest Pain and Numbness Headaches with a Pacemaker

Single Most Likely Diagnosis

  • Pacemaker Syndrome: This condition occurs when the pacemaker does not synchronize properly with the heart's natural rhythm, leading to symptoms such as chest pain, headaches, and numbness. Given the patient's pacemaker and normal EKG, this diagnosis is highly plausible.

Other Likely Diagnoses

  • Anxiety or Panic Disorder: These conditions can cause chest pain and headaches, and the numbness could be related to hyperventilation or anxiety-induced paresthesia.
  • Gastroesophageal Reflux Disease (GERD): GERD can cause chest pain and headaches, and the numbness could be related to referred pain or anxiety.
  • Hypertension: Uncontrolled high blood pressure can cause headaches and chest pain, and the numbness could be related to hypertensive encephalopathy or atherosclerotic disease.

Do Not Miss Diagnoses

  • Pulmonary Embolism: Although the EKG is normal, a pulmonary embolism can cause chest pain and numbness, and it is essential to rule out this potentially life-threatening condition.
  • Aortic Dissection: This condition can cause chest pain and numbness, and it is crucial to consider it, especially in patients with a history of hypertension or aortic disease.
  • Cardiac Ischemia: Although the EKG is normal, cardiac ischemia can cause chest pain, and it is essential to consider this diagnosis, especially in patients with a history of coronary artery disease.

Rare Diagnoses

  • Neurocardiogenic Syncope: This condition can cause numbness, headaches, and chest pain, and it is related to abnormal heart rate and blood pressure regulation.
  • Mitral Valve Prolapse: This condition can cause chest pain, headaches, and numbness, and it is essential to consider it, especially in patients with a history of mitral valve disease.
  • Arrhythmia: Although the EKG is normal, certain arrhythmias, such as atrial fibrillation or ventricular tachycardia, can cause chest pain and numbness, and it is essential to consider these diagnoses, especially in patients with a pacemaker.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.