From the Research
BPC-157 should not be used as a medication due to insufficient clinical evidence supporting its safety and efficacy, despite some promising results in animal studies and limited human trials, as evidenced by the most recent study in 2025 1.
Background
BPC-157 (Body Protection Compound-157) is a synthetic peptide derived from a protective protein found in gastric juice. While some preliminary research suggests potential benefits for tissue healing, gut health, and inflammation reduction, these studies are primarily in animals with very limited human clinical trials.
Current Evidence
The most recent study in 2025 1 assessed the safety of intravenous infusion of BPC-157 in humans and found no adverse effects. However, this study had a small sample size and was not designed to evaluate efficacy. Another study in 2021 2 found that intra-articular injection of BPC-157 helped relieve knee pain in 87.5% of patients, but this was a retrospective study with limited follow-up.
Risks and Uncertainties
Using BPC-157 carries unknown risks due to the lack of proper quality control, standardized dosing protocols, or comprehensive safety data. Side effects may include nausea, dizziness, gastrointestinal discomfort, and potential unknown long-term effects.
Recommendation
If you're dealing with an injury or condition that might make BPC-157 seem appealing, I strongly recommend consulting with a healthcare provider about evidence-based, approved treatment options instead. While BPC-157 may have potential benefits, the current evidence is insufficient to support its use as a medication, and more research is needed to fully understand its safety and efficacy, as noted in studies 3, 4, 5.