From the Research
Pistachios are unlikely to significantly increase uric acid levels for most people. They contain moderate amounts of purines, which are compounds that break down into uric acid in the body, but their purine content is lower than many animal proteins and certain other foods 1. Pistachios also offer beneficial nutrients like protein, healthy fats, fiber, and antioxidants that may actually help with overall health. For individuals with gout or hyperuricemia (high uric acid levels), moderation is key - consuming pistachios in reasonable portions (about 1 ounce or a small handful daily) should not cause problems for most people.
Key Considerations
- The overall diet pattern matters more than any single food, so focusing on a balanced diet low in high-purine foods (like organ meats, some seafood, and beer) is crucial 2.
- Maintaining proper hydration and taking prescribed medications as directed are more important factors in managing uric acid levels 3.
- Those with severe gout or recurring attacks might consider limiting pistachio consumption and monitoring their symptoms.
Management of Uric Acid Levels
- Reducing uric acid levels is key to avoiding gout flares, and medications like allopurinol and febuxostat can be effective in achieving this goal 4, 3.
- A study published in 2022 found that allopurinol and febuxostat achieved serum urate goals in patients with gout, with allopurinol being noninferior to febuxostat in controlling flares 3.