From the Guidelines
Avobenzone does not cause cancer, and its use in sunscreens is considered safe and effective in preventing skin cancer. Based on the available evidence, there is no conclusive link between avobenzone and cancer 1. The U.S. Preventive Services Task Force recommends the use of sunscreens, including those containing avobenzone, as a preventive measure against skin cancer 1. While the study notes that the use of sunscreens can extend the duration of intentional sun exposure, which may increase the risk for cutaneous melanoma, it does not specifically implicate avobenzone as a carcinogen 1. Some key points to consider include:
- Avobenzone is an FDA-approved sunscreen ingredient that absorbs UVA rays, which contribute to skin aging and can increase the risk of skin cancer.
- Epidemiological studies have not found evidence linking avobenzone to cancer in humans.
- The benefits of using sunscreens containing avobenzone to protect against UV radiation, a known carcinogen, far outweigh any theoretical risks.
- Avobenzone is sometimes combined with other UV filters in sunscreen formulations to provide broad-spectrum protection.
- Mineral-based alternatives containing zinc oxide or titanium dioxide are available for those with concerns about chemical sunscreen ingredients, though avobenzone remains recognized as safe and effective by major regulatory bodies worldwide.
From the FDA Drug Label
Uses • helps prevent sunburn • if used as directed with other sun protection measures (see Directions), decreases the risk of skin cancer and early skin aging caused by the sun The FDA drug label does not answer the question.
From the Research
Avobenzone and Cancer Risk
- There is no direct evidence in the provided studies that suggests avobenzone causes cancer 2, 3, 4, 5, 6.
- Avobenzone is a UVA filter used in sunscreen formulations to provide broad-spectrum protection against UV radiation, which is a recognized prime carcinogen 2, 3, 4.
- The studies focus on the photostability and efficacy of avobenzone in providing UVA protection, as well as its potential photodegradation and phototoxic effects 3, 4.
- Other sunscreen ingredients, such as oxybenzone, have been linked to potential human health risks and environmental concerns, but avobenzone is not mentioned as a carcinogen in these studies 5, 6.
Safety Aspects of Avobenzone
- Avobenzone has been shown to be effective in providing UVA protection when formulated with sound formulation strategies to minimize its photodegradation 3, 4.
- The use of photostabilizers and other formulation ingredients can help maintain the photostability of avobenzone and ensure its continued efficacy in providing broad-spectrum protection 3, 4.
- There is no mention of avobenzone being a human health risk or a carcinogen in the provided studies, but its potential phototoxic effects and photodegradation are discussed 3, 4.