What is the appropriate dose of Alkaline Citrate for kidney stones?

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Last updated: February 22, 2025View editorial policy

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From the Research

The recommended dose of alkaline citrate for kidney stones is typically 60 mEq/day, as this dose has been shown to effectively increase urinary citrate and pH, reduce stone formation, and prevent new stone formation in patients with hypocitraturia and other abnormalities 1, 2. To use:

  • Mix the powder with water or other liquid
  • Take with meals
  • Continue treatment for at least 3-6 months, or as directed by your doctor
  • Drink plenty of water throughout the day This medication works by making the urine more alkaline, which helps dissolve certain types of kidney stones and prevents new ones from forming. The citrate also binds to calcium in the urine, reducing stone formation. It's essential to follow up with your doctor regularly while taking this medication to monitor its effectiveness and adjust the dose if needed. Some patients may require long-term treatment to prevent stone recurrence. Key points to consider:
  • The dose of 60 mEq/day is supported by studies that demonstrate its efficacy in preventing new stone formation and reducing stone recurrence 1, 2
  • Potassium citrate is an effective treatment for patients with uric acid nephrolithiasis, as it increases urinary pH and reduces undissociated uric acid 2
  • The medication should be taken with meals to minimize gastrointestinal side effects
  • Regular follow-up with your doctor is crucial to monitor the effectiveness of the treatment and adjust the dose as needed
  • Patients should drink plenty of water throughout the day to help prevent stone formation and reduce the risk of recurrence 3

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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