What is the most likely cause of sudden-onset chest pain and shortness of breath in a 16-year-old male with a murmur and radiating pain to the neck and jaw?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 30, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Sudden-Onset Chest Pain in a 16-Year-Old Boy

Single Most Likely Diagnosis

  • Aortic dissection or related aortic pathology: The patient's symptoms of sudden-onset chest pain radiating to the neck and jaw, along with a murmur and physical examination findings of mild scoliosis and pectus carinatum, suggest a possible underlying connective tissue disorder such as Marfan syndrome. This condition increases the risk of aortic dissection.

Other Likely Diagnoses

  • Acute pericarditis: The patient's chest pain and shortness of breath could be indicative of pericarditis, especially if there's an associated pericardial friction rub, which is not mentioned but should be considered.
  • Myocardial infarction: Although less common in teenagers, myocardial infarction should be considered, especially if there are risk factors such as hypercoagulable states or severe hypertension.

Do Not Miss Diagnoses

  • Dissecting aortic aneurysm: This is a life-threatening condition that requires immediate diagnosis and treatment. The patient's symptoms and physical findings make this a critical diagnosis not to miss.
  • Pulmonary embolism: Although less likely given the patient's age and presentation, pulmonary embolism is a potentially fatal condition that must be considered, especially if there are underlying risk factors for thromboembolism.
  • Spontaneous pneumothorax: Given the patient's physical characteristics (tall and thin), spontaneous pneumothorax is a possibility, especially if the patient has underlying lung disease.

Rare Diagnoses

  • Spontaneous coronary artery dissection: This is a rare cause of myocardial infarction that could present with sudden chest pain.
  • Mitral valve prolapse with associated complications: While mitral valve prolapse is not uncommon, complications such as severe mitral regurgitation or chordae tendineae rupture could present acutely and require urgent attention.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.