Is hyperbaric oxygen therapy (HBOT) effective for asthma treatment?

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Last updated: May 30, 2025View editorial policy

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From the Guidelines

Hyperbaric oxygen therapy is not recommended for asthma treatment due to insufficient evidence supporting its effectiveness and potential risks associated with its use. The current guidelines for managing asthma exacerbations, as outlined in the National Asthma Education and Prevention Program Expert Panel Report 3 1, emphasize the importance of primary treatments such as administration of oxygen, inhaled β2-agonists, and systemic corticosteroids. These treatments have been proven to be effective in reducing airway inflammation and improving breathing in patients with asthma.

Some key points to consider in the management of asthma exacerbations include:

  • The use of inhaled corticosteroids, such as fluticasone and budesonide, to reduce airway inflammation
  • The administration of bronchodilators, such as albuterol and salmeterol, to relax airway muscles
  • The potential use of biologics, such as omalizumab and dupilumab, in severe cases of asthma
  • The importance of monitoring patient response to treatment and adjusting therapy as needed

In contrast, hyperbaric oxygen therapy (HBOT) involves breathing pure oxygen in a pressurized chamber, which has not been proven to be effective in reducing inflammation or improving symptoms in patients with asthma 1. Additionally, HBOT carries risks including ear and sinus pain, temporary nearsightedness, claustrophobia, and rarely, oxygen toxicity or lung damage. Therefore, patients with asthma should work with their healthcare providers to develop an appropriate treatment plan using evidence-based medications and strategies rather than pursuing HBOT as an alternative therapy.

From the Research

Hyperbaric Oxygen Therapy for Asthma Treatment

  • There is limited research directly addressing the use of hyperbaric oxygen therapy for asthma treatment 2.
  • Most studies focus on the use of inhaled corticosteroids and long-acting beta-agonists for managing asthma, with no mention of hyperbaric oxygen therapy 3, 4, 5, 6.
  • Hyperbaric oxygen therapy has been explored for various applications, including hypoxic regions, and exerting antimicrobial, immunomodulatory, and angiogenic properties 2.
  • The potential benefits of hyperbaric oxygen therapy for inflammatory and systemic maladies are being researched, but its specific application for asthma treatment is not well-studied 2.

Current Asthma Treatments

  • Inhaled corticosteroids and long-acting beta-agonists are commonly used to manage asthma, with combination therapy often preferred for moderate to severe cases 3, 4, 5, 6.
  • The combination of an inhaled corticosteroid and a long-acting beta-agonist in a single inhaler is considered a safe and effective treatment option for asthma management 3, 6.

Need for Further Research

  • There is a need for further research on the potential applications of hyperbaric oxygen therapy, including its use in asthma treatment 2.
  • More studies are required to fully understand the safety and effectiveness of hyperbaric oxygen therapy for various conditions, including asthma 2.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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