What is the cause of a painful axillary mass in a 5-year-old child without discharge or surrounding erythema?

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Differential Diagnosis for a 5-year-old with a Painful Bump Under the Arm

  • Single most likely diagnosis
    • Infected lymph node or lymphadenitis: This is a common condition in children, where a lymph node becomes infected, usually due to a bacterial or viral infection. The presence of a painful bump under the arm without discharge or surrounding erythema could indicate an infected lymph node.
  • Other Likely diagnoses
    • Cat scratch disease: This is a bacterial infection caused by Bartonella henselae, typically transmitted through a cat scratch or bite. It often presents with a painful lymph node, usually in the axilla, which matches the symptoms described.
    • Furuncle or carbuncle: Although less likely without surrounding erythema, a furuncle (boil) or carbuncle (cluster of boils) could present as a painful bump under the arm. These are usually caused by Staphylococcus aureus.
    • Hidradenitis suppurativa: This chronic skin condition involves recurrent, painful abscesses and nodules in areas of the body with apocrine sweat glands, such as the axillae. However, it's less common in young children.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Tuberculosis (TB) lymphadenitis: Although less common, TB can cause lymphadenitis, which might present similarly. Given the potential severity and need for specific treatment, it's crucial not to miss this diagnosis.
    • Malignancy (e.g., lymphoma): While rare in children, lymphoma could present with lymphadenopathy (enlarged lymph nodes) that might be painful. Early diagnosis is critical for effective treatment.
  • Rare diagnoses
    • Lipoma or other benign tumors: These could present as a bump under the arm but are typically painless.
    • Cystic hygroma or other congenital anomalies: These are rare conditions that could present as a mass in the axillary region but are usually identified earlier in life.
    • Actinomycosis: A rare bacterial infection that can cause abscesses or masses in various parts of the body, including the axilla, but this would be an unusual presentation.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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