From the FDA Drug Label
Studies in healthy volunteers show that in single high doses lorazepam has a tranquilizing action on the central nervous system with no appreciable effect on the respiratory or cardiovascular systems.
The FDA drug label does not answer the question about Ativan (lorazepam) and palpitations, as it only mentions that lorazepam has no appreciable effect on the cardiovascular systems in healthy volunteers, but does not specifically address palpitations. 1
From the Research
Ativan (lorazepam) can potentially cause palpitations as a side effect, and if you're experiencing palpitations while taking Ativan, you should contact your healthcare provider promptly to discuss these symptoms. If you are taking Ativan and experiencing palpitations, it is crucial to consult your healthcare provider to determine the best course of action. The provider may consider adjusting your dosage or switching medications to better manage your symptoms. Some key points to consider when evaluating palpitations in the context of Ativan use include:
- The potential for Ativan to affect the cardiovascular system, particularly in individuals with pre-existing heart conditions
- The role of anxiety and the autonomic nervous system in contributing to palpitations
- The importance of ruling out other potential causes of palpitations, such as caffeine consumption, other medications, or underlying heart conditions According to a study published in 2022 2, beta-blockers have been shown to be effective in treating arrhythmias, including palpitations. This study suggests that beta-blockers may be a useful alternative or adjunct to Ativan in managing palpitations, particularly in patients with anxiety disorders. Another study from 2019 3 highlights the antiarrhythmic mechanisms of beta-blocker therapy, which may be relevant to patients experiencing palpitations while taking Ativan. Overall, the management of palpitations in patients taking Ativan requires a comprehensive approach that takes into account the individual's medical history, the potential effects of Ativan on the cardiovascular system, and the role of anxiety and other factors in contributing to palpitations. Your doctor may recommend additional testing or adjustments to your treatment plan to ensure the best possible outcomes in terms of morbidity, mortality, and quality of life.