What is the differential diagnosis for a patient with a history of liver and pancreas laceration from a Motor Vehicle Collision (MVC) presenting with sudden onset abdominal pain, without recent trauma or injury, and no pertinent past medical history?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 30, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Abdominal Pain

The patient has a history of liver and pancreas laceration from a motor vehicle collision (MVC) in February and is now presenting with abdominal pain. Given the sudden onset of pain without recent trauma or injury, and no pertinent past medical history aside from the previous injuries, the following differential diagnoses are considered:

  • Single Most Likely Diagnosis

    • Pancreatic pseudocyst: This condition is a likely complication of the previous pancreatic laceration. A pseudocyst can form weeks to months after the initial injury, causing abdominal pain due to its size or potential rupture.
  • Other Likely Diagnoses

    • Adhesions or bowel obstruction: Previous abdominal surgery or trauma can lead to the formation of adhesions, which may cause bowel obstruction, presenting as abdominal pain.
    • Liver abscess or infection: Given the history of liver laceration, there's a possibility of an abscess or infection in the liver, which could cause abdominal pain.
    • Cholecystitis: Inflammation of the gallbladder could be a cause of abdominal pain, especially if there was any injury to the biliary system during the MVC.
  • Do Not Miss Diagnoses

    • Hemorrhage from previous laceration sites: Although less likely given the time frame, it's crucial not to miss a potential hemorrhage from the liver or pancreatic laceration sites, as it could be life-threatening.
    • Perforated viscus: A perforation in the gastrointestinal tract, potentially from a previous injury or new trauma, is a medical emergency that requires immediate attention.
    • Mesenteric ischemia: Reduced blood flow to the intestines could be a complication of the previous trauma or a new event, leading to severe abdominal pain and potentially life-threatening consequences if not addressed promptly.
  • Rare Diagnoses

    • Pancreatic fistula: An abnormal connection between the pancreas and other organs or the skin could be a rare complication of the pancreatic laceration, leading to abdominal pain and other symptoms.
    • Arteriovenous fistula: A rare complication of vascular injury during the MVC, leading to an abnormal connection between arteries and veins, which could cause abdominal pain among other symptoms.
    • Splenic vein thrombosis: Although the spleen was not mentioned as being injured, splenic vein thrombosis could be a rare cause of abdominal pain, especially if there was any injury to the spleen or its vessels during the MVC.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.