From the Guidelines
Endomycin is not recommended for gout treatment. The standard medications for acute gout attacks include colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs) like naproxen or indomethacin, and corticosteroids, as recommended by the American College of Physicians 1. For long-term management, medications that lower uric acid levels are typically used to prevent future attacks.
Key Points to Consider
- Gout occurs when uric acid crystals accumulate in joints, causing inflammation and pain.
- Effective treatments either reduce inflammation during acute attacks or lower uric acid levels to prevent future attacks.
- The American College of Physicians recommends choosing corticosteroids, NSAIDs, or colchicine to treat patients with acute gout, with a strong recommendation and high-quality evidence 1.
- Endomycin, which appears to be a misspelling or uncommon term, is not a recognized medication for gout in standard treatment guidelines.
Treatment Approach
If you're experiencing gout symptoms, consult with a healthcare provider who can prescribe appropriate medication based on your specific situation, medical history, and any other medications you may be taking. The healthcare provider will discuss the benefits, harms, costs, and individual preferences with you before initiating any therapy, including concomitant prophylaxis, in patients with recurrent gout attacks 1.
From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
Treatment Options for Gout
- Gout is a common form of acute inflammatory arthritis caused by the deposition of monosodium urate crystals within synovium of joints, leading to severe pain and reduced quality of life 2.
- Standard pharmacotherapies for gout flares include colchicine, NSAIDs, and oral or intramuscular corticosteroids, with IL-1 inhibitors as an option for flare refractory to standard therapies 2, 3.
- Urate-lowering therapies aim to prevent gout flares, with an emphasis on treat-to-target strategy, and initial treatments include allopurinol and febuxostat 2, 4, 3.
Urate-Lowering Therapies
- Allopurinol is an effective treatment for reducing concentrations of uric acid, and renal function guides the starting dose of allopurinol 4.
- Febuxostat is another xanthine oxidase inhibitor, clinically equivalent to allopurinol 4.
- Uricosuric drugs, such as probenecid, increase uric acid excretion, and new drugs in this class are likely to have a role in the treatment of patients who do not respond to other drugs 4.
Emerging Therapies
- Novel uricosurics, such as verinurad and arhalofenate, are agents with future promise 3.
- Pegloticase is effective for patients with recalcitrant gout, but its immunogenicity significantly threatens the achievement of sustained urate lowering responses 3.
- Lesinurad, in combination with xanthine oxidase inhibitors, is a new treatment option for patients with refractory gout 5.