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Differential Diagnosis for Knee Swelling

  • Single most likely diagnosis
    • Prepatellar Bursitis: This condition is likely given the patient's history of frequent kneeling, which can cause irritation and inflammation of the prepatellar bursa. The presence of a lump on the bottom of the kneecap, which filled back up after attempted drainage, and the associated redness, swelling, and warmth, are consistent with this diagnosis.
  • Other Likely diagnoses
    • Septic Bursitis: The patient's attempt to drain the area and the presence of blood and fluid, along with the worsening symptoms of redness, swelling, and warmth, could indicate a septic bursitis, which is an infection of the bursa.
    • Hemorrhagic Bursitis: The presence of blood after attempted drainage could also suggest a hemorrhagic bursitis, which is a collection of blood in the bursa.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Deep Vein Thrombosis (DVT): Although less likely, the patient's symptoms of redness and swelling extending down to the foot could be indicative of a DVT, which is a blood clot in the deep veins of the leg. This condition can be life-threatening if not promptly diagnosed and treated.
    • Cellulitis: The patient's symptoms of redness, swelling, and warmth could also indicate cellulitis, a bacterial skin infection that can spread rapidly and become severe if not treated promptly.
  • Rare diagnoses
    • Synovial Chondromatosis: This is a rare condition characterized by the growth of cartilage in the synovial membrane of the joint, which can cause swelling and a lump. However, it is less likely given the patient's symptoms and history.
    • Gout or Pseudogout: These conditions are characterized by sudden, severe joint pain and swelling, but are less likely given the patient's symptoms and history of frequent kneeling.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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