From the Research
Cellular angiofibroma is a rare, benign soft tissue tumor that typically occurs in the genital region of both men and women, characterized by a mixture of spindle cells and small blood vessels, as reported in the most recent study 1. The recommended treatment for cellular angiofibroma is complete surgical excision, which involves removing the entire tumor with clear margins to prevent recurrence, as supported by the latest evidence 1. No additional therapies like radiation or chemotherapy are typically necessary.
Key Points for Management
- Diagnosis is usually confirmed through biopsy and histopathological examination, with immunohistochemical analysis revealing positive results for CD34 and vimentin, as noted in 1.
- Imaging studies like MRI may be used to determine the extent of the tumor before surgery, as seen in 1.
- Follow-up appointments are important to monitor for any potential recurrence, though this is rare, as reported in 1.
The tumor is generally slow-growing and does not metastasize, with its benign nature justifying a conservative surgical approach, as emphasized in 1. Patients should be reassured about the generally excellent prognosis following complete excision, but advised to report any new growths in the area promptly to their healthcare provider, as recommended in 1.
Additional Considerations
- The tumor can occur in various locations, including the vulva, hypopharynx, and extragenital areas, as reported in 2 and 3.
- Complete local excision of the tumor is usually curative, with no recurrence after surgery, as noted in 4 and 5.
- The patient's age, medical history, and symptoms should be taken into account when diagnosing and managing cellular angiofibroma, as seen in 1 and 5.