From the Research
The recommended treatment for Group B Streptococcal (GBS) pneumonia is intravenous penicillin G or ampicillin, with penicillin G being the preferred choice due to its efficacy and the universal susceptibility of GBS to penicillins 1.
Treatment Options
- For penicillin G, the typical dosage is 3-4 million units every 4 hours, as this dosing interval ensures anti-GBS activity in all patients 2.
- Ampicillin is usually administered at 2 grams every 4-6 hours.
- Treatment duration typically ranges from 10-14 days, depending on clinical response.
Alternative Therapies
- For patients with penicillin allergies, alternatives include ceftriaxone (1-2 grams daily) or vancomycin (15-20 mg/kg every 8-12 hours) 3.
- In severe cases, particularly in neonates or immunocompromised patients, combination therapy with an aminoglycoside like gentamicin (5-7 mg/kg daily) may be added for synergistic effect.
Supportive Care
- Supportive care including oxygen therapy, respiratory support, and management of complications is essential.
- GBS pneumonia can progress rapidly, especially in vulnerable populations like neonates and the elderly, making prompt treatment crucial 1.