From the Guidelines
No, there is no scientific evidence that shiitake mushrooms can kill Human Papillomavirus (HPV). While shiitake mushrooms do contain compounds with some immune-boosting and antiviral properties, including lentinan and other polysaccharides, they have not been proven effective against HPV in clinical studies 1. HPV infections are best addressed through established medical approaches, including vaccination (Gardasil 9 or Cervarix) for prevention, which is recommended for adolescents and young adults before exposure to the virus. For existing HPV infections, treatment depends on whether there are symptoms or abnormal cell changes. Most HPV infections clear naturally within 1-2 years through the body's immune response. If abnormal cell changes or warts develop, medical treatments such as cryotherapy, laser therapy, or surgical removal may be necessary.
Some key points to consider:
- HPV is a common sexually transmitted virus, and most people will get it at some point in their lives 1
- There is no cure for HPV, but the body's immune system can suppress the virus, and most people will not develop symptoms 1
- Treatment for HPV-related lesions, such as genital warts, can reduce but probably not eliminate infectiousness 1
- Maintaining a healthy immune system through good nutrition, including a balanced diet, may support the body's natural ability to fight infections, but shiitake mushrooms should not be relied upon as a treatment for HPV.
It's essential to prioritize established medical approaches for preventing and treating HPV infections, rather than relying on unproven remedies like shiitake mushrooms. The most effective way to prevent HPV is through vaccination, and treatment should be guided by a healthcare professional.
From the Research
Shiitake Mushrooms and HPV
- There is no direct evidence in the provided studies that Shiitake mushrooms can kill Human Papillomavirus (HPV) 2, 3, 4, 5.
- However, a study found that consuming Lentinula edodes (Shiitake) mushrooms daily can improve human immunity, including increased ex vivo proliferation of γδ-T and NK-T cells, and improved gut immunity 6.
- This improved immunity may potentially help the body to fight against HPV infection, but there is no direct evidence to support this claim.
- The provided studies mainly focus on the treatment of cervical intraepithelial neoplasia (CIN) using various methods such as LEEP, cryotherapy, and cold knife conization, and do not discuss the effect of Shiitake mushrooms on HPV 2, 3, 4, 5.