From the Research
In Italy, the equivalent to ibuprofen is also called ibuprofen, marketed under brand names such as Moment, Brufen, and Nurofen. These medications contain the same active ingredient as ibuprofen products found in other countries and are used for the same purposes - reducing pain, inflammation, and fever. The standard dosage for adults is typically 200-400mg taken every 6-8 hours as needed, not exceeding 1200mg in 24 hours without medical supervision, as supported by the Italian experts' consensus statements 1.
Key Points to Consider
- These medications are available over-the-counter in Italian pharmacies (farmacie), which can be identified by green cross signs throughout cities and towns.
- When purchasing, you can simply ask for "ibuprofene" if you need the generic version.
- Like all NSAIDs, Italian ibuprofen should be taken with food to reduce stomach irritation, and should be avoided by those with certain conditions including stomach ulcers, severe heart failure, or kidney problems, due to the potential for adverse effects as discussed in 2.
- The medication works by inhibiting cyclooxygenase enzymes that produce inflammatory prostaglandins, thereby reducing inflammation and associated pain.
- It's worth noting that combining acetaminophen and NSAIDs for mild-to-moderate pain may have potential advantages, including greater efficacy and fewer adverse events, as suggested by 3 and 4, but this should be considered on a case-by-case basis.
Important Safety Information
- Patients should be aware of the potential risks associated with NSAID use, including gastrointestinal, cardiovascular, and renal complications, as highlighted in 2.
- Therefore, it is crucial to follow the recommended dosage and consult a healthcare professional if necessary, especially for patients with pre-existing conditions or those taking other medications.