Differential Diagnosis for Sore Lips
- Single most likely diagnosis
- Cheilitis: This is the most common cause of sore lips, often due to dryness, cold weather, or excessive licking of the lips. It can also be caused by vitamin deficiencies or allergic reactions.
- Other Likely diagnoses
- Cold sores (Herpes Simplex): These are small, fluid-filled blisters that appear on the lips, often caused by the herpes simplex virus. They can be painful and may recur.
- Angular cheilitis: This condition causes red, swollen patches in the corners of the mouth, often due to a fungal or bacterial infection.
- Dry lips (Chapped lips): Prolonged exposure to dry air, cold weather, or wind can cause dry, cracked lips.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Oral cancer: Although rare, oral cancer can cause sore lips, especially if there is a persistent ulcer or lesion. Early detection is crucial for effective treatment.
- Autoimmune disorders (e.g., lupus, pemphigus): These conditions can cause sore lips, as well as other systemic symptoms. Prompt diagnosis and treatment are essential to prevent complications.
- Rare diagnoses
- Actinic cheilitis: A precancerous condition caused by prolonged sun exposure, leading to dry, scaly lips.
- Allergic contact cheilitis: An allergic reaction to certain substances, such as toothpaste, cosmetics, or food, can cause sore lips.
- Erythema multiforme: A rare skin condition characterized by target-shaped lesions on the lips and other parts of the body, often triggered by infections or medications.