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Last updated: June 2, 2025View editorial policy

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Differential Diagnosis for Headache

  • Single most likely diagnosis
    • Tension headache: This is the most common type of headache and is often described as a band or a squeezing sensation around the forehead, usually accompanied by muscle tension in the neck and scalp.
  • Other Likely diagnoses
    • Migraine: Characterized by severe, throbbing pain, often unilateral, and can be accompanied by nausea, vomiting, and sensitivity to light and sound.
    • Sinus headache: Caused by inflammation or infection of the sinuses, leading to pain and pressure in the face and forehead.
    • Cluster headache: Extremely painful, occurs in cycles or clusters, and is often accompanied by nasal congestion and eye watering on the affected side.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Subarachnoid hemorrhage: A life-threatening condition caused by bleeding into the space surrounding the brain, often presenting with a sudden, severe headache.
    • Meningitis: Inflammation of the protective membranes covering the brain and spinal cord, which can be caused by infection and is characterized by headache, fever, and stiff neck.
    • Temporal arteritis: Inflammation of the blood vessels in the temple, which can lead to blindness if not treated promptly, and is often accompanied by headache, jaw claudication, and visual disturbances.
  • Rare diagnoses
    • Trigeminal neuralgia: A chronic pain condition that affects the trigeminal nerve, causing intense, shock-like or stabbing pain in parts of the face.
    • Idiopathic intracranial hypertension: A condition characterized by increased pressure within the skull without any apparent cause, leading to headache, vision changes, and tinnitus.
    • Hypnic headache: A rare type of headache that occurs only during sleep and wakes the patient up, typically occurring in older adults.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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