From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
Fungal rashes in the armpits and groin can be effectively treated with antifungal medications and proper hygiene, with itraconazole being the most effective oral antifungal agent, as shown in a study published in 2020 1. These rashes typically present as red, itchy, sometimes scaly patches with well-defined borders, often with central clearing creating a ring-like appearance. They thrive in warm, moist environments, which is why they commonly affect skin folds. For treatment, over-the-counter topical antifungals like clotrimazole 1% (Lotrimin), miconazole 2% (Monistat), or terbinafine 1% (Lamisil) should be applied twice daily for 2-4 weeks, continuing for at least one week after the rash resolves to prevent recurrence. Some key points to consider when treating fungal rashes include:
- Keeping the affected areas clean and dry
- Wearing loose-fitting cotton underwear and clothing
- Changing clothes after sweating
- Using separate towels for the affected areas
- Avoiding potential allergens in antifungal creams, such as propylene glycol, which is commonly found in ketoconazole 2% and miconazole nitrate 2% creams 2
- Being aware of the potential for antifungal hypersensitivity reactions and cross-reactivity patterns 3 For severe or persistent cases, prescription-strength topicals like ketoconazole 2% cream or oral medications such as fluconazole 150mg weekly for 2-4 weeks may be necessary, although itraconazole has been shown to be more effective than fluconazole in some studies 1, 4. If the rash doesn't improve within two weeks of treatment, worsens, or is accompanied by fever or significant pain, consult a healthcare provider as it may indicate a different condition or complication. It's also important to note that the effectiveness of antifungal agents can vary depending on the specific type of fungal infection and the individual patient, so it's essential to work with a healthcare provider to determine the best course of treatment. In general, the goal of treatment is to alleviate symptoms, prevent recurrence, and improve quality of life, while also minimizing the risk of adverse effects and promoting good hygiene practices to prevent the spread of infection.