What is the first line treatment for allergies in a 6 year old child?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: June 3, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

The first line treatment for allergies in a 6-year-old child is typically a second-generation oral antihistamine such as cetirizine (Zyrtec), loratadine (Claritin), or fexofenadine (Allegra). For cetirizine, the recommended dose is 5-10 mg once daily; for loratadine, 5 mg once daily; and for fexofenadine, 30 mg twice daily. These medications are preferred because they cause less sedation than first-generation antihistamines and don't require multiple daily doses.

Key Considerations

  • For nasal symptoms, intranasal corticosteroids like fluticasone (Children's Flonase) at 1-2 sprays per nostril daily may be added.
  • For eye symptoms, antihistamine eye drops such as ketotifen (Zaditor) can be used, typically 1 drop in each affected eye twice daily.
  • It's essential to use these medications consistently during allergy season rather than as needed.
  • These medications work by blocking histamine receptors or reducing inflammation, which are key mechanisms in allergic reactions.
  • If symptoms persist despite these treatments, the child should be evaluated by a healthcare provider as additional or alternative treatments may be necessary, as supported by studies such as 1.

From the FDA Drug Label

Pediatric patients (4 years of age and older) should be started with 100 mcg (1 spray in each nostril once daily). Treatment with 200 mcg (2 sprays in each nostril once daily or 1 spray in each nostril twice daily) should be reserved for pediatric patients not adequately responding to 100 mcg daily The first line treatment for allergies in a 6 year old child is fluticasone at a dose of 100 mcg (1 spray in each nostril once daily) 2.

  • The dose can be increased to 200 mcg (2 sprays in each nostril once daily or 1 spray in each nostril twice daily) if the child does not respond to the initial dose.
  • It is essential to monitor the child's growth regularly while using this medication, as intranasal corticosteroids may cause a reduction in growth velocity in pediatric patients 2.

From the Research

First-Line Treatment for Allergies in Children

The first-line treatment for allergies in a 6-year-old child typically involves the use of antihistamines or intranasal corticosteroids, depending on the severity and frequency of symptoms.

  • For mild intermittent or mild persistent allergic rhinitis, a second-generation H1 antihistamine (eg, cetirizine, fexofenadine, desloratadine, loratadine) or an intranasal antihistamine (eg, azelastine, olopatadine) may be recommended 3, 4.
  • For persistent moderate to severe allergic rhinitis, an intranasal corticosteroid (eg, fluticasone, triamcinolone, budesonide, mometasone) is often the first-line treatment, either alone or in combination with an intranasal antihistamine 3, 5.
  • Second-generation oral antihistamines, such as cetirizine, desloratadine, and fexofenadine, have been shown to relieve symptoms of nasal congestion and are considered safe for use in children 4, 6.
  • Intranasal corticosteroids, like fluticasone propionate, are effective in reducing nasal symptom scores and are often recommended for moderate to severe allergic rhinitis 5, 7.

Considerations for Treatment

When selecting a treatment, it's essential to consider the severity and frequency of symptoms, as well as patient preference and any potential side effects.

  • Antihistamines are commonly used to treat allergic rhinitis in children, but it's crucial to choose the right type and dosage to minimize adverse effects 6.
  • Intranasal corticosteroids are generally well-tolerated, but patients should be instructed on proper use and potential side effects 3, 5.
  • Combination therapy, such as using an intranasal corticosteroid with an oral antihistamine, may be effective for some patients, but should be tailored to individual needs 5, 7.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Treatment of allergic rhinitis.

The American journal of medicine, 2002

Research

Antihistamines: ABC for the pediatricians.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2020

Research

Comparative nasal airflow with loratadine-pseudoephedrine and fluticasone nasal spray for allergic rhinitis.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.