What is the appropriate volume of D5 (Dextrose) in 1/2 NS (Normal Saline) for a 72-year-old male patient with hypernatremia, hypochloremia, and hyperkalemia?

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Last updated: February 23, 2025 • View editorial policy

From the Research

The most appropriate volume of D5 in 1/2 NS for a 72-year-old male patient with hypernatremia, hypochloremia, and hyperkalemia is not directly supported by the provided evidence, but based on general medical knowledge, administering 1000 mL of D5 in 1/2 NS over 8-12 hours is a reasonable approach to help correct the electrolyte imbalances while minimizing the risk of fluid overload.

Administration Details

  • Solution: D5 in 1/2 NS
  • Volume: 1000 mL
  • Rate: Infuse over 8-12 hours (about 83-125 mL/hour)
  • Monitor: Check serum electrolytes every 4-6 hours ### Rationale The provided evidence does not directly address the question of fluid management in a patient with hypernatremia, hypochloremia, and hyperkalemia. However, based on general medical principles, the goal is to correct the electrolyte imbalances while avoiding fluid overload, especially in an elderly patient 1. D5 in 1/2 NS can help provide free water to correct hypernatremia and some electrolytes to address hypochloremia and hyperkalemia. The slow infusion rate allows for careful monitoring and adjustment of therapy as needed.

Additional Considerations

  • Closely monitor for signs of fluid overload, especially given the patient's age
  • Assess for underlying causes of electrolyte imbalances (e.g., medications, renal issues)
  • Consider nephrology consult if electrolyte imbalances persist or worsen
  • Adjust subsequent fluid therapy based on repeat electrolyte measurements and clinical response Note: The evidence provided does not directly support the recommendation, but it is based on general medical knowledge and principles of fluid and electrolyte management.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.