From the Research
It is generally safe to take Linzess (linaclotide) and sildenafil (Viagra) together as there are no known significant drug interactions between these medications. Linzess is a medication used to treat irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation, while sildenafil is used for erectile dysfunction and pulmonary arterial hypertension. These medications work through different mechanisms in the body - Linzess acts locally in the intestines to increase intestinal fluid secretion and movement, while sildenafil works by increasing blood flow to specific areas of the body by inhibiting an enzyme called phosphodiesterase type 5 (PDE5) 1.
However, it's essential to consider the potential side effects of each medication. Linzess can cause diarrhea, while sildenafil can cause headaches, dizziness, and flushing 2, 3. Individual responses can vary, and some people might experience increased side effects when taking these medications together.
Both medications should be taken as prescribed - Linzess on an empty stomach at least 30 minutes before the first meal of the day, and sildenafil typically 30-60 minutes before sexual activity. Despite the general safety of combining these medications, it's always best to consult with your healthcare provider before taking them together, especially if you have underlying health conditions or are taking other medications 4, 5.
Some key points to consider when taking Linzess and sildenafil together include:
- Monitoring for increased side effects such as diarrhea, headaches, and dizziness
- Taking the medications as prescribed to minimize potential interactions
- Consulting with a healthcare provider before starting or stopping either medication
- Being aware of any underlying health conditions that may affect the safety of combining these medications.