From the Research
The treatment for Majocchi's granuloma should involve oral terbinafine as the first-line agent, given its efficacy and safety, as demonstrated in the most recent study 1. The choice of terbinafine is based on its ability to effectively penetrate the hair follicles and surrounding dermis, where the fungal infection is located.
- The dosage of terbinafine is typically 250 mg daily, administered for a duration of 4-8 weeks, depending on the clinical response of the patient.
- In cases where the patient has severe or resistant disease, or is immunocompromised, longer treatment courses of 8-12 weeks may be necessary.
- It is essential to discontinue any topical or systemic corticosteroids, as these can exacerbate the infection.
- Surgical drainage may be considered in rare cases where large fluctuant lesions are present.
- Clinical improvement should be regularly monitored, and treatment should continue until complete resolution of the lesions to prevent recurrence, as supported by the findings of 1 and 2.
- The use of oral terbinafine has been shown to achieve clinical resolution in a high percentage of cases, as reported in 1, making it the preferred treatment option for Majocchi's granuloma.