Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: June 4, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Left Lower Quadrant (LLQ) Pain

  • Single Most Likely Diagnosis
    • Diverticulitis: This is a common cause of LLQ pain, especially in older adults, due to inflammation of the diverticula in the sigmoid colon.
  • Other Likely Diagnoses
    • Constipation: Hard stools or difficulty passing stools can cause pain in the LLQ due to the location of the sigmoid colon and rectum.
    • Irritable Bowel Syndrome (IBS): Abdominal pain, including LLQ pain, is a common symptom of IBS, often accompanied by changes in bowel habits.
    • Ovarian Cyst or Torsion: In females, ovarian cysts or torsion can cause severe LLQ pain, often sudden in onset.
    • Kidney Stone: A stone in the left ureter can cause severe pain that radiates to the LLQ.
  • Do Not Miss Diagnoses
    • Ectopic Pregnancy: Although less common, ectopic pregnancy is a life-threatening condition that can present with LLQ pain and must be ruled out in females of childbearing age.
    • Appendicitis (if appendix is located in the LLQ): Although appendicitis typically presents with right lower quadrant pain, an appendix located in the LLQ can cause pain in this area.
    • Intestinal Obstruction: Obstruction of the intestine can cause severe abdominal pain, including LLQ pain, and is a medical emergency.
    • Inflammatory Bowel Disease (IBD): Conditions like Crohn's disease or ulcerative colitis can cause chronic LLQ pain and changes in bowel habits.
  • Rare Diagnoses
    • Colonic Volvulus: A twisting of a portion of the colon can cause severe abdominal pain, including LLQ pain, and is more common in older adults.
    • Endometriosis: Although more commonly associated with pelvic pain, endometriosis can cause LLQ pain in some cases, especially if endometrial implants are located near the sigmoid colon.
    • Lymphoma: Abdominal lymphoma can cause LLQ pain due to the involvement of lymph nodes in the area.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.