From the FDA Drug Label
DIRECTIONS Follow dosage below or use as directed by a physician. do not take more than 6 doses in any 24-hour period. age dose adults and children 12 years and over10 to 20 mL (2 to 4 teaspoonfuls) every 4 hours children 6 years to under 12 years5 to 10 mL (1 to 2 teaspoonfuls) every 4 hours children 2 to under 6 years of age2.5 to 5 mL (½ to 1 teaspoonful) every 4 hours children under 2 years of ageconsult a physician
The recommended dose and frequency of Mucinex (Guaifenesin) liquid are:
- Adults and children 12 years and over: 10 to 20 mL (2 to 4 teaspoonfuls) every 4 hours
- Children 6 years to under 12 years: 5 to 10 mL (1 to 2 teaspoonfuls) every 4 hours
- Children 2 to under 6 years of age: 2.5 to 5 mL (½ to 1 teaspoonful) every 4 hours
- Children under 2 years of age: consult a physician 1
From the Research
The recommended dose of Mucinex (guaifenesin) liquid for adults and children 12 years and older is 200-400 mg every 4 hours, not exceeding 2,400 mg in 24 hours, as supported by the study 2.
Key Considerations
- For children 6-11 years old, the recommended dose is 100-200 mg every 4 hours, not exceeding 1,200 mg daily.
- Children 2-5 years old should take 50-100 mg every 4 hours, with a maximum of 600 mg daily.
- Mucinex liquid should be measured using the provided dosing cup or spoon for accuracy, and taken with a full glass of water.
Mechanism of Action
- This medication works as an expectorant by thinning mucus in the airways, making coughs more productive and helping clear congestion, as described in the study 2.
Important Notes
- Different Mucinex formulations contain varying concentrations of guaifenesin, so always check the specific product label.
- If symptoms persist beyond 7 days, worsen, or are accompanied by fever, consult a healthcare provider.
- Those with persistent cough, chronic respiratory conditions, or who are pregnant or breastfeeding should speak with their doctor before using this medication.
Evidence Quality
- The study 2 provides the most recent and highest quality evidence for the recommended dose and frequency of Mucinex liquid.
- Other studies, such as 3, 4, 5, and 6, provide additional information on the efficacy and safety of guaifenesin, but are not as directly relevant to the recommended dose and frequency.