There are no official guidelines to assist in answering this question. I will search for relevant research papers instead.
From the Research
Administration of Steroids for Influenza in Asthma Patients
- The use of corticosteroids in patients with asthma is well-established, but their administration in the context of influenza is more complex 1, 2.
- A study comparing oral and intravenous steroids in acute exacerbation of asthma found similar efficacy between the two routes of administration, suggesting that oral steroids may be a viable option for patients with asthma 1.
- However, the use of corticosteroids in severe influenza pneumonia has been questioned, with some studies suggesting that it may increase overall mortality and have no beneficial effects 2.
- In patients with asthma, inhaled corticosteroids (ICS) do not appear to increase the risk of influenza, according to a meta-analysis of randomized controlled trials 3.
- Vaccination against influenza is an important consideration for patients with asthma, and studies have shown that influenza vaccines are safe and effective in this population, even during acute asthma exacerbations and concurrent prednisone therapy 4, 5.
Considerations for Steroid Administration
- The decision to administer steroids for influenza in a patient with a history of asthma should be made on a case-by-case basis, taking into account the severity of the influenza infection and the patient's asthma status 2.
- The potential benefits and risks of steroid administration should be carefully weighed, considering the potential for increased mortality and other adverse effects 2.
- Alternative treatments, such as antiviral medications and supportive care, may be preferred in some cases 2.
- Vaccination against influenza should be considered as a preventive measure for patients with asthma, to reduce the risk of influenza infection and exacerbation of asthma symptoms 4, 5.