Finding Donanemab Treatment Centers
Contact specialty dementia clinics, academic medical centers, or memory care centers in your area, as donanemab (Kisunla) infusions are primarily administered in specialty clinical practices with comprehensive multidisciplinary teams and appropriate monitoring capabilities.
Where to Look for Treatment Centers
The availability of donanemab requires healthcare systems with specific infrastructure and expertise 1:
- Specialty clinical practices - Memory clinics and dementia specialty centers are the primary sites offering these infusions
- Academic medical centers - University-affiliated hospitals with neurology departments
- Regional medical centers - Larger healthcare systems with infusion capabilities and MRI monitoring 2
Why Specialty Centers Are Required
Donanemab administration requires high proficiency and sufficient resources including close collaborations with comprehensive multidisciplinary teams 1. These centers must have:
- Infusion capabilities - IV infusion administered every 4 weeks over approximately 30 minutes 3
- MRI monitoring - Brain MRI required for monitoring amyloid-related imaging abnormalities (ARIA) 1
- Experienced staff - Trained in managing potential infusion reactions and ARIA complications
- Biomarker testing - Ability to confirm amyloid pathology before treatment initiation 4
Practical Steps to Find a Center
- Ask your primary care physician for referral to dementia specialists who offer disease-modifying therapies
- Contact local academic medical centers - Call neurology or memory disorder clinics directly
- Use the Alzheimer's Association - They maintain resources on treatment availability (though not explicitly stated in guidelines, this is standard practice)
- Check with regional specialty medical centers that have established donanemab programs 2
Important Considerations
There are too few specialists currently available to respond to the possible number of patients who are candidates for treatment 1, 5. This means:
- Expect wait times - Prolonged waits are common for specialty dementia care 4
- Hub-and-spoke models emerging - New partnerships between community organizations, primary care clinicians, and specialists are being developed 1, 5
- Geographic limitations - Not all areas have immediate access to these specialized services
What the Center Will Require
Before treatment can begin, you'll need:
- Confirmed diagnosis of early symptomatic Alzheimer's disease (mild cognitive impairment or mild dementia) 4, 3
- Biomarker confirmation of amyloid pathology via PET scan, CSF testing, or blood-based biomarkers 4
- Baseline brain MRI to screen for contraindications like cerebral amyloid angiopathy 6
- APOE genotyping (influences ARIA risk and treatment eligibility in some regions) 1
Healthcare systems around the country are actively working to establish these treatment pathways, but infrastructure is still developing 1, 5. Start by contacting the largest medical centers in your region with established neurology or memory disorder programs.