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Last updated: June 4, 2025View editorial policy

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Differential Diagnosis for Plantar Fibroma

  • Single most likely diagnosis
    • Plantar fibroma: This is the most likely diagnosis due to the specific location and nature of the condition. Plantar fibromas are benign growths that occur on the plantar surface of the foot, often causing discomfort or pain.
  • Other Likely diagnoses
    • Plantar fasciitis: Inflammation of the plantar fascia can cause similar symptoms to plantar fibroma, such as pain and discomfort on the bottom of the foot.
    • Morton's neuroma: A benign growth that occurs between the toes, causing pain, numbness, or tingling in the foot.
    • Lipoma: A benign tumor composed of fat tissue that can occur on the plantar surface of the foot, causing discomfort or pain.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Soft tissue sarcoma: Although rare, soft tissue sarcomas can occur on the plantar surface of the foot and have a poor prognosis if not diagnosed and treated promptly.
    • Invasive fungal infection: Certain fungal infections, such as madura foot, can cause lesions or growths on the foot that may resemble a plantar fibroma.
  • Rare diagnoses
    • Plantar ganglioneuroma: A rare, benign tumor that occurs on the plantar surface of the foot, composed of nerve tissue.
    • Giant cell tumor of the tendon sheath: A rare, benign tumor that can occur on the plantar surface of the foot, causing pain and discomfort.
    • Epidermal inclusion cyst: A rare, benign cyst that can occur on the plantar surface of the foot, causing discomfort or pain.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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