Do I apply Dermabond (2-octyl cyanoacrylate) before or after Steri-Strips (reinforced adhesive strips) for laceration closure?

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Last updated: February 23, 2025View editorial policy

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From the Guidelines

For laceration closure, apply Steri-strips before Dermabond. This approach allows for precise wound edge approximation with the Steri-strips, followed by the application of Dermabond as a reinforcing layer to provide additional protection and security to the wound closure 1.

Key Considerations

  • Clean and dry the wound thoroughly before applying Steri-strips to ensure proper adhesion and minimize the risk of infection.
  • Apply Steri-strips across the laceration, ensuring accurate wound edge approximation to facilitate optimal healing.
  • Once the Steri-strips are in place, apply a thin layer of Dermabond liquid adhesive over the Steri-strips and surrounding skin, extending about 1-2 cm beyond the wound edges to reinforce the closure.
  • Allow the Dermabond to dry completely, which usually takes about 30 seconds, to ensure it forms a strong and protective barrier over the wound.

Benefits of This Approach

  • Enhances wound closure strength by combining the mechanical closure of Steri-strips with the adhesive properties of Dermabond.
  • Reduces the risk of infection by providing a protective barrier over the wound.
  • Minimizes pain and anxiety associated with laceration repair, as both Steri-strips and Dermabond are essentially painless when applied correctly 1.

Important Precautions

  • Avoid getting Dermabond into the wound itself, as this can interfere with the healing process.
  • Ensure the wound is clean, dry, and free of debris before applying Steri-strips and Dermabond to optimize the effectiveness of the closure and minimize complications.

From the Research

Application of Dermabond and Steri-Strips

  • The order of application of Dermabond (2-octyl cyanoacrylate) and Steri-Strips (reinforced adhesive strips) for laceration closure is not explicitly stated in the provided studies 2, 3, 4, 5, 6.
  • However, a study comparing the cosmetic outcomes of simple facial lacerations closed with Steri Strip Skin Closures or Dermabond found that both methods provided similar cosmetic outcomes 4.
  • Another study compared the wound-bursting strengths of octyl-cyanoacrylate (Dermabond), butyl-cyanoacrylate, and surgical tape (Steri-Strips) in rats, and found that Dermabond had a higher wound-bursting strength than Steri-Strips 5.
  • A review of wound management options discussed the use of staples, sutures, Steri-Strips, and tissue adhesives (such as Dermabond) for wound closure, but did not specify the order of application 6.
  • A study on the management of pretibial lacerations described a technique using deep reinforced suturing through Steri-Strips, but did not mention the use of Dermabond 2.
  • Another study presented a technique using a combination of Steri-Strips and sutures for the management of lacerations in thin-skinned individuals, but also did not mention the use of Dermabond 3.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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